- Brandywine Valley SPCA, New Castle
- 600 South Street, New Castle, DE 19720
- https://bvspca.org
- 302 516-1000
- Brandywine Valley SPCA, Georgetown
- 22918 DuPont Boulevard, Georgetown, DE 19947
- https://bvspca.org
- 302 856-6361
- Delaware Humane Association
- 701 A Street, Wilmington, DE 19801
- https://delawarehumane.org/
- 302 571-0111
- Faithful Friends Animal Society
- 12 Germay Drive, Wilmington, DE 19804
- www.faithfulfriends.us/
- 302 427-8514
- Forgotten Cats
- 4023 Kennett Pike, Suite 422, Greenville, DE 19807
- http://forgottencats.org/index.php
- 302 429-0124
- Grass Roots Rescue
- Lewes, DE
- http://www.grrde.org